FEATURES OF THE EFFECTIVENESS OF TREATING SEASONAL ALLERGIC RHINITIS IN THE METROPOLIS
Keywords:
allergic rhinitis, mometasone furoate, fluticasone furoate, levocetirizine.Abstract
Introduction. The most effective treatments for allergic rhinitis are oral antihistamines and intranasal corticosteroids; however, there is evidence that corticosteroids are superior due to better symptom relief in patients.
Objective. To evaluate the efficacy of two second-generation antihistamines (cetirizine and levocetirizine) and two nasal corticosteroids (mometasone and fluticasone furoate) in patients with allergic rhinitis and to compare clinical outcomes.
Material and methods. 288 patients with allergic rhinitis living in Almaty treated with cetirizine, levocetirizine, mometasone furoate or fluticasone furoate were included in the study. Treatment efficacy was assessed using the total nasal symptom score (TNSS), where scores ranged from 0 to 12, where 0 meant no symptoms.
Results and discussion. All patients underwent a three-month follow-up. Of them, 75% were taking antihistamines, 20% were taking corticosteroids, and 5% were taking combination drugs. The mean TNSS score was 2.5 for corticosteroids, 5 for antihistamines, and 4 for combination drugs. Differences between the efficacy of taking corticosteroids and antihistamines were found.
Conclusion. Second-generation oral antihistamines are more frequently prescribed in the treatment of allergic rhinitis than topical intranasal corticosteroids. However, patients treated with corticosteroids showed better control of allergic rhinitis symptoms.
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