ETORICOXIB IN THE TREATMENT OF PATIENTS WITH NEUROLOGICAL AND RHEUMATOLOGIC DISEASES. CONSENSUS OF THE EXPERT COUNCIL

Authors

  • Andrei B DANILOV I.M. Sechenov First Moscow State Medical University (Sechenov University), Doctor of Medical Sciences, Professor of the Department of Nervous Diseases of the Faculty of Postgraduate Professional Education, Project Manager of “Manage Pain”
  • Galymzhan A TOGIZBAYEV Medical Partners Korea” Medical Center, Director, Doctor of Medical Sciences, Professor, Chairman of the “Kazakh Collegium of Rheumatology” RPA, General Director, Honorary Professor of Xinjiang Medical University
  • Bakhtiyar G GAFUROV Tashkent Institute for Advanced Training of Physicians, Doctor of Medical Sciences, Professor, Head of the Department of Neurology, Chief neurologist of the Ministry of Health of the Republic of Uzbekistan
  • Gulnaz S KAISHIBAYEVA Institute of Neurology and Neurorehabilitation n.a. Smagul Kayshibaev, Director, Candidate of Medical Sciences (PhD), Deputy Chairman of the “League of Neurologists Prim” NGO
  • Ulugbek K KAYUMOV Tashkent Institute for Advanced Training of Physicians, Doctor of Medical Sciences, professor, Head of the Department of Internal Medicine-1, Member of the European Federation of Internal Medicine (EFIM), Russian Scientific Medical Society of Physicians (RSMSP) and the Association of Physicians of Uzbekistan
  • LarissAnra B KUANOVA University Medical Center” Corporate Foundation, Doctor of Medical Sciences of the Russian Federation and the Republic of Kazakhstan
  • Lyubov A KUZINA Institute of Neurology and Neurorehabilitation n.a. Smagul Kayshibaev
  • Olga V MASHKUNOVA Asfendiyarov Kazakh National Medical University, Candidate of Medical Sciences, Professor of the Department of Internal Medicine, Rheumatologist of the Highest Category, Leading Consultant of the Scientific Research Institute of Cardiology and Internal Medicine of the Ministry of Health of the Republic of Kazakhstan
  • Hilola T MIRAKHMEDOVA Tashkent Medical Academy, Doctor of Medical Sciences, Head of the Department of Propedeutics of Internal Diseases No. 1, Chief Consultant for Rheumatology of the Ministry of Health of the Republic of Uzbekistan
  • Mashkhura Z RIZAMUKHAMEDOVA Tashkent Medical Academy

DOI:

https://doi.org/10.31082/1728-452X-2021-225-3-8-19

Keywords:

etoricoxib, osteoarthritis, rheumatoid arthritis, coxibs, selective NSAIDs

Abstract

In November 2020, an international virtual meeting of the Expert advisory board was held which brought together leading neurology, rheumatology, and therapy experts from Russia, Kazakhstan and Uzbekistan.
The purpose of the meeting. To determine the place of etoricoxib in the treatment of rheumatolo-
gical and neurological diseases accompanied by pain syndrome, to evaluate the efficacy and safety data for the molecule.
Modern rheumatology has made tremendous strides in the treatment of the most common autoimmune diseases, primarily, osteoarthritis and rheumatoid arthritis. The introduction of biologic drugs into clinical practice and the strategy of early aggressive therapy using basic anti-inflammatory drugs have made it possible to achieve sustained clinical remission in a significant proportion of patients. Nevertheless, symptomatic pain relievers retain their most important position in this pathology. However, the use of traditional NSAIDs is associated with adverse events, especially gastrointestinal ones. Coxibs make it possible to solve this medical problem to some extent due to their selectivity. Among coxibs, it is etoricoxib
that has a special position. On the one hand, it is a potent and reliable product for the treatment of pain with a high level of evidence in clinical practice, and on the other hand, it is well tolerated and has a minimal gastropathy risk.

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Published

2021-12-15

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