ҚАЗАҚСТАНДА АЯҚ ВАРИКОЗЫНЫҢ СЫРҚАТТАНУШЫЛЫҒЫНЫҢ ӨҢІРЛІК ЕРЕКШЕЛІКТЕРІ
##semicolon##
https://doi.org/10.31082/1728-452X-2020-217-218-7-8-2-7##semicolon##
аяқтың варикозы##common.commaListSeparator## ауру##common.commaListSeparator## Қазақстан##article.abstract##
Diseases of the cardiovascular system remain an important medical and social problem throughout the world, since the prevalence, features of the clinical course and outcomes lead to a significant decrease in the quality of life. The study of the geographic variability of varicose veins of the lower extremities (hereinafter – VLE) can expand the understanding of this problem.
Objective. To assess the regional features of the incidence of VLE in Kazakhstan for 2009-2018.
Material and methods. The material for the study was the data of the Ministry of Health of the Republic of Kazakhstan – annual form No. 12, concerning VLE (ICD 10 – I83) for 2009-2018. A retrospective study using descriptive and analytical methods of biomedical statistics was used as the main method.
Results and discussion. For 2009-2018 in the republic 158 151 cases of VLE were registered for the first time, of which 37 670 (23.8%) in men and 120 481 (76.2%) in women. The average annual incidence rate of VLE (both sexes) in the republic was 91.6±9.6 per 100,000 of the total population (95% CI=72.8-110.30/0000). The lowest incidence rates of VLE in the entire population were established in Aktobe region – 28.1±1.40/0000 (95% CI=25.4-30.80/0000). Very high incidence rates (both sexes) were detected in North Kazakhstan region (130.5±7.60/0000, 95% CI=115.6-145.40/0000) and in Astana city (163.0±11.00/0000, 95% CI=130.6-195.40/0000).
Conclusions. The study showed a preliminary assessment of VLE incidence in the republic, identifying regions of low and high frequency, trends of VLE morbidity.
In dynamics, morbidity rates tended to grow. With the equalization of the incidence rates of VLE, the average annual growth rate was Т=+12.5%.
##submission.citations##
Горелик С.Г., Литинский А.В., Поляков П.И. Варикозная болезнь нижних конечностей, особенности у лиц старших возрастных групп // Фундаментальные исследования. – 2012. – №5 (2) – P. 276-280.
Eberhardt R.T., Raffetto J.D. Chronic venous insufficiency // Circulation. – 2014. – Vol. 130 (4). – Р. 333-46. DOI: 10.1161/CIRCULATIONAHA.113.006898
Nitin J., Abhishai B., Mohamed F.T., Uma D.M., Ayesha A., Isha J. A multicenter review of epidemiology and management of varicose veins for national guidance // Annals of Medicine Surgery (Lond). – 2016. – No 8. – Р. 21–27. DOI: 10.1016/j.amsu.2016.04.024
Piazza G. Varicose veins // Circulation. – 2014. – 130(7). –
Р. 582-587. DOI: 10.1161/CIRCULATIONAHA.113.008331
Hamdan A. Management of varicose veins and venous insufficiency // JAMA. – 2012. – Vol. 308 (24). – Р. 2612–2621. DOI: 10.1001/jama.2012.111352.
Fukaya E., Flores A.M., Lindholm D., Gustafsson S., Zanetti D., Ingelsson E., Leeper N.J. Clinical and Genetic Determinants of Varicose Veins // Circulation. – 2018. – Vol.138 (25). – Р. 2869-2880. DOI: 10.1161/CIRCULATIONAHA.118.035584
Cires-Drouet R.S., Fangyang L., Rosenberger S., Startzel M., Kidwell M., Yokemick J., McDonald T., Carlin M., Sharma J., Sorkin J.D., Lal B.K. High prevalence of chronic venous disease among health care workers in the United States // J Vasc Surg Venous Lymphat Disord. – 2020. – Vol. 8 (2). – Р. 224-230. DOI: 10.1016/j.jvsv.2019.10.017
Rabe E., Berboth G., Pannier F. Epidemiology of chronic venous diseases // Wien Med Wochenschr. – 2016. – 166(9-10). –
Р. 260-263. DOI: 10.1007/s10354-016-0465-y
Zolotukhin I.A, Seliverstov E.I., Shevtsov Y.N, Avakiants I.P., Nikishkov A.S., Tatarintsev A.M., Kirienko A.I. Prevalence and Risk Factors for Chronic Venous Disease in the General Russian Population // Eur J VascEndovasc Surg. – 2017. – Vol. 54 (6). – Р. 752-758. DOI: 10.1016/j.ejvs.2017.08.033
Мерков А.М., Поляков Л.Е. Санитарная статистика – Л.: Медицина, 1974. – 384 с.
Гланц С. Медико-биологическая статистика / пер. с анг. – М.: Практикa, 1998. – 459 с.
Toshiro Tango. Statistical Methods for Disease Clustering. – Springer-Verlag New York, LLC, 2010. – 240 p.
Shadrina A.S., Sharapov S.Z., Shashkova T.I., Tsepilov Y.A. Varicose veins of lower extremities: Insights from the first large-scale genetic study // PLoS Genet. –2019. – Vol. 15(4). – e1008110. DOI: 10.1371/journal.pgen.1008110
Feodor T., Baila S., Mitea I.-A., Branisteanu D.-E., Vittos O. Epidemiology and clinical characteristics of chronic venous disease in Romania // Exp Ther Med. – 2019. – Vol. 17 (2). – P. 1097-1105. DOI: 10.3892/etm.2018.7059
