МЕНИНГОЭНЦЕФАЛИТПЕН АССОЦИИРЛЕНГЕН COVID-19 КЛИНИКАЛЫҚ ЖАҒДАЙЫ
Кілттік сөздер:
COVID-19, коронавирустық инфекция, менингоэнцефалит, неврологиялық белгілер, SARS-CoV-2, балалар.Аннотация
Өзектілігі. 2019 жылы әлем бұрын зерттелмеген инфекциямен бетпе-бет келді, пандемия қалаларды, елдерді бірінен соң бірін қамтыды және бірнеше ай ішінде бүкіл әлемге кесірін тигізді. SARS-CoV-2 инфекциясы туралы алғашқы есептерден бері covid-19 эпидемиологиялық аспектілеріне, соның ішінде клиникалық көріністер мен нәтижелерге қатысты көптеген зерттеулер жарияланды. Бұл зерттеулердің көпшілігі респираторлық асқынуларға бағытталған. Дегенмен, соңғы нәтижелер вирустың жүйелік әсерін, соның ішінде оның жүйке жүйесіне ықтимал әсерін анықтады.
Зерттеу мақсаты зерттеу. Балада COVID-19 инфекциясының неврологиялық асқынуларының клиникалық көрінісін сипаттау
Материал және әдістері. Клиникалық неврологиялық зерттеу, нейробейнелеу (мидың МРТ), иммундық-ферменттік талдау әдісі арқылы вирусологиялық зерттеу.
Нәтижелер. Кешенді зерттеу нәтижелері бойынша диагноз қойылды: нейроинфекция нәтижесінде мидың органикалық зақымдануы (ВЭБ+КВИ-мен біріктірілген), энцефалиттің мультифокальды ошақтары, соның ішінде көптеген тамырлы тромбоздар және сагиттальды синус тромбозы ПВЛ-мен біріктірілген. Псевдобульбарлық синдром. Өрескел дистония синдромы. Локализацияланған симптоматикалық эпилепсия. Екі көздің оптикалық нервінің ішінара атрофиясы.
Талқылауы. COVID-19 тек жүйке жүйесіне ғана емес, сонымен қатар ішкі мүшелерге тамырларда және басқа да өмірлік маңызды жүйелерде ауыр асқынулар тудыратыны туралы аз айтылып жатқан жоқ. Қазақстанда, сондай-ақ басқа елдерде COVID-19 неврологиялық асқынулары деректер жиынтығы мен зерттеу сатысында тұр. Әр түрлі елдердің дәрігерлері COVID-19 тек респираторлық инфекция ғана емес, сонымен қатар көп жүйелі ауру екенін мойындайды, сондықтан іс жүзінде оның әртүрлі салдарымен бетпе-бет келуге болады. Осындай жағдайлардың бірі-паллиативті көмек мәселесін шешу қажеттілігіне дейін ауруы асқынған осы бала.
Қорытынды. Барлық деректерді, оның ішінде жас балалардың ОЖЖ-нің анатомиялық-физиологиялық ерекшеліктерін ескере отырып қорытынды жасайтын болсақ, ми тіндерінің жаппай қабыну реакцияларына бейімділік және процестің тез дамуы жоққа шығарылмайды.
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