ASSESSMENT OF REPRODUCTIVE FUNCTION OF WOMEN WHO HAVE SURVIVED COVID-19

Abstract

Introduction. Coronavirus disease (Covid-19) which has been planetary in nature since 2019 has had a negative impact on public health. The impact of Covid-19 on women's reproductive health is also a hot topic among researchers in the last 5 years post Covid-19, as there are mixed opinions of researchers on the impact of coronavirus infection on women's reproductive organs.
Objective of the study. To assess the impact degree of coronavirus infection on the reproductive function of women.
Material and methods. The study included 180 women of reproductive age, the main group consisted of 90 women with moderate to severe coronavirus infection, confirmed case of Covid-19: positive PCR RNA SARSCoV-2, lower respiratory tract lesions (Covid-associated pneumonia) according to CT 1-4. The control group consisted of 90 women who were not infected with coronavirus infection.
Results. The mean age of the patients was 31±9 years. The analysis showed that women who had undergone coronavirus infection had reproductive disorders such as menstrual disorders, difficulties with pregnancy conception, and high rates of spontaneous miscarriages after coronavirus infection.
Discussion. This study shows that moderate to severe coronavirus infection can affect reproductive health. Menstrual irregularities observed in 68.8% of patients may be due to the effects of the virus on the hypothalamic-pituitary-ovarian system. The obtained results demonstrated the correlation between coronavirus infection and difficulties with conception in the studied groups of patients.
Conclusions. The results of the present study indicate statistically significant effects of Covid-19 on the female reproductive system. Covid-19 infection potentially results in menstrual irregularities, adversely affects pregnancy and increases the risk of spontaneous miscarriage.